The Expression of Carbonic Anhydrase in Canine Mammary Gland and Mammary Gland Tumor
نویسندگان
چکیده
منابع مشابه
Canine Mammary Gland Cancer Stem Cell and its Potential Role in Malignant Biologic Behavior
BACKGROUND:Canine mammary gland cancers are the most prevalent malignancies in dogs. There are different challenges regarding management of these cancers in dogs and human, one hypothesis is related to small cellular subset of tumor mass called cancer stem cell. These cells are therapy resistant and cause metastasis and relapse even after primary successful treatment. The well-identified phenot...
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CHIP (Carboxy terminus of Hsc70 Interacting Protein) is an E3 ubiquitin ligase that can induce ubiquitination and degradation of several oncogenic proteins. The expression of CHIP is frequently lower in human breast cancer than in normal breast tissue. However, the expression and role of CHIP in the canine mammary gland tumor (CMGT) remain unclear. We investigated the potential correlation betw...
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BACKGROUND Mammary tumors are the most common tumor type in intact female dogs. Recently, the breast cancer 2 early onset (BRCA2) gene was proposed to be associated with tumorigenesis in dogs. The expression level of BRCA2 is important for its DNA repair function in mammalian cells, and its expression level is linked to tumorigenesis in mammary tissue. However, the expression of canine BRCA2 in...
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Objective- This study refers to the role of ultrasonography in the diagnosis of mammary gland tumor in bitches as a complementary diagnostic method and its ultimate goal is to evaluate the results of mammography with the positive results of ultrasonography. Design- Prospective study. Animals- 12 German Shepherd bitches with swollen mass in the mammary gland region (group I) and 12 h...
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To examine the behavior of tumor cells in tumors developing directly from mammary tissue in transgenic models, we have evaluated transgenic mice expressing green fluorescent protein (GFP). Using the mouse mammary virus promoter (MMTV) to directly drive expression of GFP, we find low levels of fluorescence in the mammary and salivary glands of transgenic animals. Using MMTV-Cre or WAP-Cre in com...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2008
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.70.437